A: A polygraph exam does not cause any direct injury to the person being tested. The only discomfort is a standard blood pressure cuff which goes on the arm (typically) and is inflated for less than five minutes at a time. There are increased stress levels during the testing process which should be considered. Some medical conditions are sensitive to increased stress levels, such as some heart conditions. Depending on the medical condition, most examiners would require an approval from the treating physician prior to conducting an exam on someone with such a condition.